Transcript Glycolysis Animation

Glycolysis Animation
http://highered.mcgrawhill.com/sites/0072507470/student_view0/chapter25/animation__ho
w_glycolysis_works.html
Bridging (Transition) Process
• Aerobic  requires O2 as final electron acceptor (happens in ETC)
• Location --inside mitochondria “One-Two Punch”
• Carbonyl group released as CO2
• NAD+ reduced to NADH
• Leaves Acetyl--picked up by CoA & becomes Acetyl CoA
• Acetyl CoA intermediate in all catabolism (esp. fats & proteins)
• Surplus of ATP  acetyl-CoA gets stored as lipid
• Little ATP  acetyl-CoA enters Krebs cycle & makes ATP
Krebs Cycle
aka Citric Acid Cycle
• Location--Matrix of
mitochondria
• Aerobic  requires
O2 as final eacceptor
• Produces:
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•
•
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CO2 (from carbonyl)
NADH
FADH2
ATP
Learning Targets
5. Compare and contrast substrate level
phosphorylation, oxidative phosphorylation, and
photophosphorylation.
Background Info:
Phosphorylation
• Transfer of phosphate group
AND energy
• Enzyme-mediated
• ATP Synthase
• ATPase
Oxidative Phosphorylation
• e- transferred to oxygen through proton pumps  builds
up proton gradient
• Generates ATP through ATP Synthase
• Occurs in inner membrane of Mitochondria
Photophosphorylation
• powered by Photosystems (found only in
chloroplasts  photosynthesis)
• Final e- acceptor is NADP+
Substrate Level Phosphorylation
• Phosphate transferred from a molecule (substrate) to ADP
• Forms ATP direct
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Electron Transport Chains
(General)
• Stepwise transfer of electrons through a series
of redox reactions
• Dehydrogenase removes 2 H atoms from
molecule  transfers 2 e- & 1 proton to NAD+
• Allows 1 H+ to diffuse into cell (building a
concentration gradient
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UNCOMFORTABLE WITH/FEEL UNSURE ABOUT!! Do
less work, not more!!!
CR: First Electron Acceptor
• NAD+ (Nicotinamide adenine dinucleotide)
• NAD+  NADH
CR: Final electron acceptor  O2