Transcript Environmental Medicine

Environmental Medicine
Dr shabeel pn
Environmental Medicine
 One’s sensitization to their environment
 Exposure does not lead to consistent
symptoms
– Randomization of symptoms can confuse the
practitioner
 Drug prescription can add to the problem
The Cause of Disease
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Genetic
Psychogenesis
Environmental
Nutrient Deficiency
Food Induced Disease
 Arthritis
– Stay away from vegetables in Nightshade
category
 Prescribe NSAIDs lead to LGS
– Celiac Disease
 Wheat intolerance
– MSG
 Retinal degeneration
– Milk induced hypochlorhydria
 Leads to nutrient deficiency
Food Toxins
Fish
Parasites
Mercury
Malachite green
Systemic Toxicity
CNS, Kidney and GI for
inorganic mercury
Mutagen
Junk Fats
Acrylamide
Trans fats
Cancer
CVD
Meat/Dairy
rBGH
Antibiotic
Cancer
Antibiotic Resistance
Fruits/Vegetable
Pesticides
Liver damage, cancer
Neuromuscular
Disorders
Artificial Sweeteners
Aspartame
Sucralose
Saccharin
Excitotoxin
Tichlorinated sugar
Maybe safe
Plastics
Dioxins
Plasticizer
Cancer
Illness Induced by Chemicals
 Plasticizers TMA (trimellitic
anhydride)…complex antigens
 Dry Cleaning Fluids…CVS
 Solvents..panic disorders
 Hydrocarbons...glomerulonephritis
 Formaldehyde..fatigue-cancer
 Pesticides..brain fog (loss concentration,
poor memory, irritability, depression)
Chemicals Everywhere
 Chemical exposure is ubiquitous and ever
increasing
 Sources other than work and environment
– Bedroom – Fabric softeners, flame retardants, dry
cleaning chemicals
– Bathroom – chlorine, cosmetics, shampoos, toothpaste,
hair products, colognes, and the like
– Kitchen – pesticides, hormones, antibiotics, cookware,
plastics, petroleum residues, trans fats, flavorings,
sweeteners
Heavy metals
Metal
Source
Effects
Mercury
Amalgams, fish and
vaccines
Neurotoxin – more toxic in
children
Lead
Water, industry and
chocolate
Cognitive, hypertension,
kidney disease
Aluminum
Antiperspirants,
cookware, antacids,
baking powder
Neurotoxin, Osteoporosis,
Anemia, Liver and Kidney
damage
Arsenic
Pesticides, lumber and
well water
Cancer, Vomiting,
Anemia, Arrhythmias,
Pins and Needle
sensitivity
Cadmium
Food, water, Cigarette
smoke, Batteries
Cancer, Kidney, Liver,
Lung and Bone damage
Every Day Exposures
Flame
Retardants
Fabric Softener
PDBE (penta- and octapolybrominated diphenyl
ether)
Brain and Thyroid
impaired development
Alphaterpineol,
chloroform, benzyl
alcohol, pentane
CNS, Mucous
membranes
Water
Chlorine
Fluoride
Trihalomethanes
Impact to endothelial cell
layer within arteries,
possible carcinogen
Shampoo
Ammonium lauryl sulfate
Ammonium xylene
sulfonate, formaldehyde
CNS, Respiration,
Lachrymators, Death
Cosmetics
Phthalates, cadmium,
Arsenic
Birth deficiencies, Male
repro, Cancer
Every Day Exposures
Air Fresheners
Formaldehyde
Phenol
Cancer; Circulatory
collapse, comma, death
Carpet Shampoo
Perchloroethylene
Ammonium Hydroxide
Cancer
Irritant/lachrymator
Dishwasher Detergents
Chlorine – dry,
concentrate
Currently the #1 cause of
child poisoning
Furniture Polish
Petroleum Distillates,
Phenol
Nitrobenzene
Pneumonitis if aspirated
to lungs
GI Injury
Toilet Cleaners
Hydrochloric Acid
Hypochlorite
Tissue Injury
Irritant gas give rise to
cough, sputum,
breathlessness - infection
Antibacterial
Triclosan
Liver damage
Every Day Exposures
Pesticides
Diazinon
Chlorinated HC
Organophosphates
Neurotoxin
carcinogenic
Flea Powder
Carbaryl, Chlordane
dicholorphene
Spermatotoxicity,
Liver, kidney, lung, eye
injury
Lice Shampoo
Lindane
Vomiting, diarrhea,
convulsions
Car Wash/Polish
Petroleum Distillates
Lachrymator
Pulmonary edema
Skin and lung cancer
Drain Cleaner
TCA, HCl, Lye
Irritants, caustic
Stricture
Mold/Mildew Cleaner
Hypochlorite
Formaldehyde
Irritant, death
Nasal sarcomas
Chemical Illness
 Free Radicals
– Phase I detoxification
– Highly reactive and destructive
– Will rip the electron from anything in its path…cell
enzymes and cell membrane
– Membranes attacked
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Dictates what goes on in the cell
Regulate calcium channels
Regulate sodium pump
Provide access to genetic material
Where endoplasmic reticulum exists
Chemical Sensitivity
 Information
– does not alert the practitioner
– live with chronic conditions
 Frustrated
– symptoms are compounded by other symptoms
 Sick Building Syndrome
– Chronic Fatigue Syndrome
 Work efficiency plummets
Suspicion
 WHY IS EVERYONE NOT AFFECTED
EQUALLY?
 Depends On:
– Genetics
– Sensitization:
 How much of what?
Unexpected Death
 The body is equipped with detox
mechanisms
 The detox mechanisms do fail
– Upon failure disease occurs
– Drugs can contribute to failure
 Proteins and enzymes break down
 Leads to tissue death
 Leads to over all death
7 Principles of Environ Medicine
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Biochemical individuality
Total load
Spreading phenomenon
Adaptation
De-adaptation
Bi-polarity
Switch phenomenon
Total Load
 Conjugates (sulfur containing compounds
that facilitate removal of xenobiotics)
– Genetic predisposition
 e.g. brown eyed individuals are mineral deficient
– In turn enzymes are not functional in purported activity
3rd Principle
 Spreading phenomenon
– Patients are reactive to xenobiotics that never before
bothered them.
– Doctors unfamiliar with chemistry of detoxification begin:
 To doubt patient motives
 Sanity of the individual
– The allopathic paradigm
 Suppress symptoms with drugs
 Chronic use of drugs no longer effective
– Recommend surgery
4th Principle
 ADAPTATION
– Chronic Disease
– The sick get sicker
– Body mechanism
 More load…more need of enzymes
 Enzyme induction
– Non-sedative antihistamines
 Enzyme induction leads to neoplasm
5th Principle
 De-Adaptation
– Phenol exposure
 Preservative in medicines
 Found in home office furnishing and cleaners
 Picked up readily by the body
 Overwhelms enzyme network for removal
 Shifted to other pathways where not completely
metabolized
6th Principle
 Bipolarity
– Same agent can cause opposite effects
– e.g. alcohol
 Initially it is stimulatory
 Once the aldehyde is produced it causes the body to
become depressed
– Outcome depends on:
 Dose
 Time frame
 Adaptive enzymes
7th Principle
 Switch Phenomenon
– Target organ switches from one to another
– e.g. asthmatic person with cardiac
abnormalities, or IBS
 One disease is active while the other is quiescent
and visa versa
– Secondary importance are the symptoms
– Primary importance is to find cause
Drug Complications
 Environmental Medicine
– Drugs contribute to symptoms
 Cumulative biochemical effect
 Cause nutrient deficiencies
– Diuretics cause hypokalemia and magnesium deficiency
 Both deficiencies lead to hypertension
 Mg deficiency leads to lipidemia and reduction of delta-6desaturase
– D-6D is crucial in fatty acid metabolism; damage
endoplasmic reticulum where detoxification takes place
– Spreading Phenomenon
Complications
 What about hobbies, chemical applications
in the home, exposures during traffic, etc.?
– Needless to say a plethora of minutia needs to
be sifted through if one is to uncover the cause
– Uncover the cause
 Reverse the symptoms
Physical Signs
 Common findings not reported:
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White fury tongue
Dark spots under the eyes
White, splitting nails
Swelling
Skin temperature
Tooth loss, amalgams, mixed oral metals
Body odor
Abnormal eye movements
Poor focusing, memory
Inability to stand on one leg or tip toes with eyes closed
(common malfunction due to pesticide exposure).
Reversal
 Bowel studies are necessary
– Rule out unsuspected inflammation
– Malabsorption with insufficient break down of
protein
– Abnormal flora
– Insufficient beneficial flora
 Bowel flora play role in metabolizing vitamins, drugs,
hormones, carcinogens, and xenobiotics.
Patient Education
 Through knowledge we are now able to
recommend:
– Remove smelly plastic mattress covers
– Foam pillows
– Water beds
– Air cleaners with particle board cabinets
– Furnishings that out-gas phenol and
formaldehyde
Physician Awareness
 Minimize the use of drugs to treat symptoms
– e.g. use of NSAIDs for osteoarthritis
 Can actually lead to rheumatoid conditions
– Arthritics are to abstain from red meat and
vegetables in nightshade category
 Potatoes, tomatoes, peppers, eggplant, chili, paprika
– Also, abstain from tobacco
Physician Awareness
 Common causes of fatigue and
depression…eating foods under the ferment
category:
– Bread, cheese, vinegar, catsup, mustard,
mayonnaise, salad dressing, alcohol, chocolate,
anything aged, pickled, or fermented
New Medical paradigm
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Include environmental toxins
Correct the cause rather than the symptom
Remove food intolerances
Laboratory analysis of the bowel and intracellular
Zn, Se, Mo, Cr, Mn, K, Cu, and folate
 Recalcitrant conditions may be from amino acid
deficiency