-Cool, cuz it turns stuff red! The halobacterium has been around for billions of years Species: H. salinarium Strain: NRC-1 Organism: Archaea (meaning: no nucleus!) Halobacterium is way cool cuz: - has to have a lot of salt to live (yum!) - found in every day objects! - attributed to spoiling - grows at a neutral pH EASY TO CULTIVATE -grows in salt - grows in neutral pH - can live in extreme conditions MODEL ARCHAEA -35% of proteins are unrelated to what is previously reported - can go through many methods of gene manipulation - utilization of amino acids THE ACTUAL SEQUENCING - Sequenced by U of Washington, U of Massachusetts, and Institute of Systems Biology - Announced the complete sequence at Oct 3, 2000 - Size: 2,571,010-bp (2630 predicted proteins) -Main Chromosome (2,014,239 bp) GC (67.9%) -Plasmid p100 (191,346 bp) GC (59.1%) -Plasmid p200 (365, 425 bp) GC (57.8%) We want to know this cuz… Halobacterium today is used to develop orally administered vaccines and to design new antibiotics Although it is a archaea, has pathways to amino acids, potassium, DNA replication/ transcription/ translation, like eukaryotes. Although the halobacterium is an archaea, it is very closely related to bacillus subtilis (which is a bacteria) Plus.. we can’t forget… it’s cool because it can turn things red!