Transcript Nonsense mutations CORRECT ANSWER

Self Assessment Question 1
• Mutations that change the nucleotide sequence
without changing the amino acid sequence are:
A. Conditional mutations
B. Silent mutations
C. Permissive mutations
D. Missense mutations
E. Nonsense mutations
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Self Assessment Question 1 Answer
• Mutations that change the nucleotide sequence
without changing the amino acid sequence are:
A. Conditional mutations
B. Silent mutations CORRECT ANSWER
C. Permissive mutations
D. Missense mutations
E. Nonsense mutations
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Self Assessment Question 2
• Base substitutions in coding regions that
result in changed amino acids are called:
A. Conditional mutations
B. Transversions
C. Missense mutations
D. Nonsense mutations
E. Silent mutations
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Self Assessment Question 2 Answer
• Base substitutions in coding regions that
result in changed amino acids are called:
A. Conditional mutations
B. Transversions
C. Missense mutations CORRECT
ANSWER
D. Nonsense mutations
E. Silent mutations
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Self Assessment Question 3
• Base substitutions that create a new
stop codon are called:
A. Transitions
B. Permissive mutations
C. Missense mutations
D. Nonsense mutations
E. Silent mutations
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Self Assessment Question 3 Answer
• Base substitutions that create a new
stop codon are called:
A. Transitions
B. Permissive mutations
C. Missense mutations
D. Nonsense mutations CORRECT
ANSWER
E. Silent mutations
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Self Assessment Question 4
• Spontaneous base substitutions are:
A. Biased in favor of transversions
B. Biased in favor of transitions
C. Unbiased (transversions and transitions are
equally frequent)
D. Silent in most of the cases
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Self Assessment Question 4 Answer
• Spontaneous base substitutions are:
A. Biased in favor of transversions
B. Biased in favor of transitions CORRECT
ANSWER
C. Unbiased (transversions and transitions are
equally frequent)
D. Silent in most of the cases
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Self Assessment Question 5
• T to C or A to G mutations are:
A. Transition mutations
B. Transversion mutations
C. Translation mutations
D. Transcription mutations
E. Conditional mutations
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Self Assessment Question 5 Answer
• T to C or A to G mutations are:
A. Transition mutations CORRECT
ANSWER
B. Transversion mutations
C. Translation mutations
D. Transcription mutations
E. Conditional mutations
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Self Assessment Question 6
• T to A or G to T mutations are:
A. Transition mutations
B. Translation mutations
C. Transcription mutations
D. Conditional mutations
E. Transversion mutations
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Self Assessment Question 6 Answer
• T to A or G to T mutations are:
A. Transition mutations
B. Translation mutations
C. Transcription mutations
D. Conditional mutations
E. Transversion mutations CORRECT
ANSWER
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Self Assessment Question 7
• If a particular mutation reverts at an unusually
high rate, the cause of the mutation is very
likely to be:
A. Deletion of a base pair
B. Formation of a pyrimidine dimer
C. Insertion of a transposable element
D. Defect in proofreading repair system
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Self Assessment Question 7 Answer
• If a particular mutation reverts at an unusually
high rate, the cause of the mutation is very
likely to be:
A. Deletion of a base pair
B. Formation of a pyrimidine dimer
C. Insertion of a transposable element
CORRECT ANSWER
D. Defect in proofreading repair system
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Self Assessment Question 8
• Ultraviolet light primarily damages
DNA by:
A. Forming pyrimidine dimers
B. Forming purine dimers
C. Alkylating DNA
D. Depurinating DNA
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Self Assessment Question 8 Answer
• Ultraviolet light primarily damages
DNA by:
A. Forming pyrimidine dimers CORRECT
ANSWER
B. Forming purine dimers
C. Alkylating DNA
D. Depurinating DNA
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Mutagenes
• Almost any kind of mutation that can be induced by a mutagen can
also occur spontaneously, but mutagens bias the types of
mutations that occur according to the type of damage to the DNA
that they produce
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Self Assessment Question 9
• Ionizing radiation damages DNA by:
A. Directly interacting with the DNA
molecule
B. Depurinating the DNA
C. Interacting with water to form reactive ions
called free radicals
D. A process called intercalation
E. Replication slippage
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Self Assessment Question 9 Answer
• Ionizing radiation damages DNA by:
A. Directly interacting with the DNA
molecule
B. Depurinating the DNA
C. Interacting with water to form reactive
ions called free radicals CORRECT
ANSWER
D. A process called intercalation
E. Replication slippage
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Self Assessment Question 10
• The activity of DNA polymerases that
removes incorrectly incorporated
nucleotides is called:
A. Proofreading repair
B. Photoreactivation repair
C. Error prone repair
D. Gap repair
E. Mismatch repair
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Self Assessment Question 10 Answer
• The activity of DNA polymerases that
removes incorrectly incorporated
nucleotides is called:
A. Proofreading repair CORRECT
ANSWER
B. Photoreactivation repair
C. Error prone repair
D. Gap repair
E. Mismatch repair
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Self Assessment Question 11
• A test for carcinogens and mutagens that looks
for an increased reversion frequency in a Hisstrain of bacteria is called the:
A. Amber test
B. Mutagen test
C. Ames test
D. Salmonella reversion test
E. Auxotrophic reversion test
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Self Assessment Question 11 Answer
• A test for carcinogens and mutagens that looks
for an increased reversion frequency in a Hisstrain of bacteria is called the:
A. Amber test
B. Mutagen test
C. Ames test CORRECT ANSWER
D. Salmonella reversion test
E. Auxotrophic reversion test
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Self Assessment Question 12
• AP repair acts on nucleotides that:
A. Underwent methylation
B. Underwent deamination
C. Lost their base
D. Are located in a displacement loop
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Self Assessment Question 12 Answer
• AP repair acts on nucleotides that:
A. Underwent methylation
B. Underwent deamination
C. Lost their base CORRECT ANSWER
D. Are located in a displacement loop
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Self Assessment Question 13
• Cancer cells are characterized by:
A. Activation of apoptosis
B. Increased contact inhibition
C. Low telomerase activity
D. Uncontrolled cellular proliferation
E. All of the above
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Self Assessment Question 13 Answer
• Cancer cells are characterized by:
A. Activation of apoptosis
B. Increased contact inhibition
C. Low telomerase activity
D. Uncontrolled cellular proliferation
CORRECT ANSWER
E. All of the above
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Self Assessment Question 14
• The major mutational target(s) for the multistep
cancer progression is:
A. Trinucleotide repeats
B. Tumor-suppressor genes
C. Proto-oncogenes
D. Telomerase
E. A and B
F. B and C
G. C and D
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Self Assessment Question 14 Answer
• The major mutational target(s) for the multistep
cancer progression is:
A. Trinucleotide repeats
B. Tumor-suppressor genes
C. Proto-oncogenes
D. Telomerase
E. A and B
F. B and C CORRECT ANSWER
G. C and D
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Questions?
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