Transcript Slide 1

Place Title Here
Resident Name
Mentor Name
Thoughts
• Remember for your project proposal, you will probably not have
results and discussion. However, you can let them know where
you are at in the process and ask for their guidance and input.
This is your opportunity to educate the faculty and your fellow
residents as to how you plan to accomplish the project. Plus, you
are drawing on the experience of others who have already been
there and done that. By involving others early in the process, you
will be able to manage the project. If not, the project will
manage you.
• If all else fails, ask for help!
More Thoughts
• As in life, there is a process/steps that we go through. Birth, childhood,
teenager, adult, elder, death (you get the idea). Currently, in this
process, you are an OBGYN resident who has the opportunity to do
research. Though research maybe relatively new to you, it has been
present since the beginning of time. Therefore cherish the fact that those
before you have already constructed a pathway for you to follow. It is call
the scientific method. These steps follow:
Stating the questions
Literature search
Objective
Design
Materials and Method
Results
Discussion
Conclusion
After you give your project proposal, you should be through the first, five
steps. In other words, your are over halfway to completion.
Rule of Thumb
• Don’t put any information
on a slide that will not fit
reasonably on a 3 X 5
index card.
Introduction
(or Background)
• Heading
– Included sub-headings1
1) Author, Year (references)
Cyr61 Structure
•
•
•
•
379 amino acids
Example
42 kDa
Cysteine rich
Encoded on chromosome 1
CCN1 0
IGFBP
VWC
TSP1
IGFBP: Insulin-like growth factor binding protein motif
VWC: von Willibrand Type C module
TSP1: thrombospondin type I repeat
CT: C--terminal module
CT
AAAA
Objectives
• To…
Materials and Methods
• Design
– Retrospective, Prospective, Cohort, Observational,
Double blind, randomized trial, survey
• Patient Demographics
– Age
– Ethnicity
– G’s and P’s.
• Methods
– Describe methods (use project protocol template)
– Inclusion/exclusion criteria
– Statistical Analysis (Power Analysis)
Study Design
PT POSTED FOR ABDOMINAL OR VAGINAL HYSTERECTOMY
NOT ELIGIBLE
ELIGIBLE
CEFAZOLIN + PLACEBO
CEFAZOLIN + METRONIDAZOLE
Cultures, Surgery
Cultures, Surgery
Postoperative Follow-up
Example
Postoperative Follow-up
Results
Regulation in Endometrium
• Western blot analysis
of ECC1 for Cyr61
– Treated with
diethylstilbestrol (DES)
– Treated with epidermal
growth factor (EGF)
Example
Results
Endometrial Adenocarcinoma
Example
Cyr61 Immunostaining
Mid-secretory
Normal endometrium
Proliferative
• Expression
increased in
endometrial
cancer
compared with
normal midsecretory
endometrium
Endometrial adenocarcinoma
Results
Endometrial Adenocarcinoma
• RT-PCR for Cyr61
in normal cycling
endometrium and in
endometrial
adenocarcinoma
(* P<0.001)
Example
Results
Table 1. Preoperative BV Status versus Postoperative
Infection Rate versus Metronidazole/Placebo
Group
BV Status
Postop
Infection
No Postop
Infection
P
Metronidazole
Positive
Intermediate
Negative
3 (17.6%)
3 (27.3%)
3 (12.5%)
14 (82.4%)
8 (72.7%)
21 (87.5%)
0.6
Placebo
Positive
Intermediate
Negative
2 (16.7%)
2 (11.1%)
6 (25.0%)
10 (83.3%)
16 (88.9%)
18 (75.0%)
0.5
Example
Discussion
• Start discussion here
Conclusions
• Start conclusions here
Future Studies
• Start future studies here
Acknowledgments
• Add acknowledgments here