Transcript Sniper and LPE

Microcatheter
With Balloon Occlusion
Improving the lives of people living with cancer
Microcatheter
With Balloon Occlusion
Superior Tracking and Pushability
Improved Tumor Fill
Reduced Non-Target
Embolization
Simple Integration
Microcatheter
With Balloon Occlusion
Superior Tracking & Pushability
Photos courtesy of Aaron Fischman, MD
Microcatheter
With Balloon Occlusion
Problems to be Solved
Embolization with a Standard Microcatheter
• The drug/embolic agent is injected under high
arterial pressure
• Drug/embolic agent delivery is random and
not reproducible
Liver
Stomach
*
Tumor
*
Flow towards
healthy tissues
Intestine
*
*
*
High
Pressure
*
*
• Does not optimally fill the tumor
retrograde flow
>
• Travels to healthy tissue via antegrade and
Injection with
Standard Catheter
Microcatheter
With Balloon Occlusion
Low Pressure Embolization (LPE)
LPE represents a paradigm
shift in standard drug-delivery for tumor therapy.
Deliver embolic agents more confidently
and with more control.
Microcatheter
With Balloon Occlusion
Low Pressure Embolization (LPE)
*
Low
*
Pressure
Embolization with a Sniper Microcatheter
• The balloon occludes the artery resulting in
low pressure near the tumor
Flow redirection
toward tumor
*
*
• Branch arteries are redirected and flow
toward the low pressure
• Drug/embolic agent flows exclusively into
*
>
the tumor since it has the lowest pressure
• Drug reaches tumor vessels
• Drug does not flow toward healthy tissue
* *
Lower
Pressure
Microcatheter
Improved Tumor Fill with LPE
Standard Microcatheter w/ Tc-99m MAA
Post-procedure SPECT Scan
Infusion with a standard high flow microcatheter
results in preferential Tc-99m MAA deposition
along the periphery of the tumor.
With Balloon Occlusion
Sniper Microcatheter with Y90
Post-procedure SPECT Scan
Infusion with an Embolx Sniper Microcathteter
yields uniform distribution of Y90 throughout
entire tumor.
Photos courtesy of Brian Kouri, MD
Microcatheter
With Balloon Occlusion
Schedule a Clinical Demonstration.
Speak to an Embolx Representive
to Learn More.
[email protected]
408.990.2949
Embolx, Inc | 740 San Aleso Ave | Sunnyvale, CA 94085
Microcatheter
With Balloon Occlusion
Improved Tumor Fill with LPE
Embosphere 100-300µ
Embozene 400µ
Embozene 250µ
InfusionType
Standard
Catheter
NSF Funded Animal Study
Study concluded that
2.4 X the amount of
embolic agents are
collected with Sniper
as compared to a
standard catheter.
Microcatheter
With Balloon Occlusion
Reduced Non-target Flow with LPE
Particle
Collection
Pseudo-Tumor
Low Pressure
Zone
Tumor
Artery
All arteries are visible
Right
Hepatic
Arteries
Left
Hepatic
Arteries
Only Tumor Artery is visible,
Only Tumor
all other arteries
flow Artery
towardis visible,
all
other
arteries
flow toward
the tumor when the
the
tumor
when
Sniper® balloon is inflated the
Tumor
Sniper® balloon is inflated
Artery
Sniper®
Balloon
NSF Funded study conducted by at UCSD by Dr. Steve Rose,
Chief of Interventional Oncology, UCSD Medical Center
Microcatheter
Simple Integration
• High performance with
comparable pricing to
standard microcatheters
• Compatible with 5Fr
diagnostic/guide catheter
• Easy to use
• Requires no additional
accessories
With Balloon Occlusion
Microcatheter
With Balloon Occlusion
What Experts are Saying:
"Bottom line, fixed temporary occlusion balloons and
dynamic anti-reflux devices for transarterial
embolization of liver tumors appear to
simultaneously improve both safety and efficacy.”
Steven C. Rose, MD FSIR
Director of Interventional Oncology
University of California, San Diego, CA
Microcatheter
With Balloon Occlusion
What Experts are Saying:
"Manipulating blood pressure and flow to improve
the tumor-killing effects of embolization therapies is
a promising new technique. Using an occlusion
balloon catheter has the potential of not only
improving outcomes, but also simplifying the
treatment technique to make this option available to
more patients and doctors."
Daniel Sze, MD PhD | Professor, Interventional Radiology
Stanford University Medical Center
Microcatheter
With Balloon Occlusion
Schedule a Clinical Demonstration.
Speak to an Embolx Representive
to Learn More.
[email protected]
408.990.2949
Embolx, Inc | 740 San Aleso Ave | Sunnyvale, CA 94085
Microcatheter
With Balloon Occlusion