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Mean arterial plasma concentration–time profiles of CZX (A) and OH-CZX (B) after p.o.
administration of CZX (50 mg/kg) to LC (▪; n = 7), DM (○; n = 8), LCD (□; n = 8), and control (•; n =
7) rats.
Choong Y. Ahn et al. Drug Metab Dispos 2008;36:1233-1241
The American Society for Pharmacology and Experimental Therapeutics