arizona_presentation_2_Dr_Glass

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Alastair M. Glass
Deputy Minister
Ontario: Uniquely Positioned
• Exceptionally strong research
base
• Strong manufacturing base
• Strong government
commitment
• Strong tradition of education
• Gateway to the US (NAFTA)
• Diverse population
• Generous R+D tax credits
The Ministry of Research
and Innovation (MRI)
• New Ministry of Research and Innovation - focus
• The Premier of Ontario is the Minister of Research
and Innovation
• The Province will invest $1.7 billion over five years
through an integrated set of research,
commercialization and outreach programs
• The Ontario Research and Innovation Council (ORIC)
will provide expert advice to the Premier
• Focus on areas of strength and opportunity
• Strategic plan launched for consultation
Ontario innovation
imperatives
• Continue to build research strength through
partnership
• Extract economic and social value from research
• Attract and build industrial research
• Build on tradition of entrepreneurship
• Forge industry-academia partnerships/clusters
• Showcase Ontario strengths and accomplishments
• Inspire the next generation of innovators
MaRS Discovery
District
Gateway to Ontario
• 1.5 million square foot
commercial development in
the heart of Toronto’s
medical research district
• US $350M public-private
partnership of researchers,
business and investors
• Ontario international
“flagship”
commercialization and
convergence center
Ontario Centres of Excellence
(OCE)
• Centre for Energy
• Communications and Information
Technology Ontario
• Earth and Environmental Technologies
• Materials and Manufacturing Ontario
• Photonics Research Ontario
Collectively, the centres promote the economic
development of Ontario through directed research,
commercialization of technology and training for
highly qualified personnel.
Nano Funding in Canada
1998-2005
– Natural Sciences and Engineering Research
Council (NSERC)
– Canadian Institutes of Health Research (CIHR)
– Canada Foundation for Innovation
– Provincial Programs
In excess of $430 million for Canada
$150 million for Ontario
Major Canadian Nano Hubs
4 major geographic clusters of nano R&D activity have
evolved organically
• Greater Toronto
Area/Southern Ontario
• Montreal/Quebec City
• Edmonton
• Vancouver
National Institute for Nanotechnology
• Federal and Alberta Governments invest $120 million for 2002
– 2006, Federal Government commits ongoing basic operating
funds of $12 million/yr starting in Year 6
• Core tools & instrumentation of NINT:
• Electron Microscopy (SEM, TEM)
• Surface and Materials Analysis
• Scanning Probe Microscopy
• Organic/Inorganic Synthesis and Analysis
• Computation and Modeling
• Optical Characterization
• Tool Development (instrumentation, software)
Nanotechnology Network Ontario (NanO)
• 5 major centres of academic activity:
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University of Toronto
McMaster University
University of Western Ontario
University of Waterloo
Queens University
• Strength in nanomaterials, nanobiotechnology, nanoelectronics,
nanophotonics, nanocharacterization
• Numerous companies with interests in nanomaterials,
nanobiotechnology, nanoelectronics and nano-energy
Canadian Centre for Electron Microscopy
at McMaster University
• $18 million facility:
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specially designed quiet space
superior temperature stability
reduced vibrations
lower noise levels and electromagnetic
field interference
Exterior of facility housing the
ultrahigh resolution transmission
electron microscope
• Includes two microscopes enabling structural, chemical and
spectroscopic information with an electron probe size smaller
than 1 Angstrom and an energy resolution of 0.1 eV
Canadian Centre for Electron Microscopy
at McMaster University
• Areas of research include:
– Materials for photonic applications (photonic crystals,
quantum dots and wells)
– Materials for nanoelectronics
– Materials for energy and environment (hydrogen
storage materials, nanoparticles for catalysis)
– Materials in health (drug delivery systems, fluorescent
tags, biosensors)
• Collaborations
– More than 100 researchers from 24 universities
across Canada and 12 National Laboratories will use
this state-of-the-art facility
– Numerous international and industrial collaborations
Titan 80-300, currently
being built for the facility
by FEI
Nanotechnology at Toronto
• Areas of research include:
– Information Technology
– Industrial and Environmental Coatings
– Energy Nanotechnologies
– Nanomedicine
– Tissue Engineering and Drug Delivery
• Numerous spin-offs, including:
3D Silicon Photonic Crystal
– Northern Nanotechnologies (inorganic quantum dot nanoparticles)
– Axela Biosensors (real-time detection of biomolecular interactions)
– BoneTec Corporation (tissue engineered bone growth)
– Matregen (targeted drug delivery)
Nanotechnology at Toronto
• Nanomedicine
– Major diseases being targeted include
cancer and heart disease
– Activities include drug discovery, disease
detection and therapeutic approaches
– There are Ontario commercial ventures in
all of these areas
• Industrial and Environmental Coatings
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monoclonal
antibody
antigen
cancer
cell
Cancer detection and therapy using
functionalized nanoparticles
Chrome replacement technology
Wear-resistant coatings for brakes
Nano coated carbon-fibre parts for durable racing parts
Flexible inorganic-organic nanoscale coatings for display technologies
Ontario is a leader in molecular medicine
• Discovery of stem cells (McCulloch and Till 1961)
• Discovery and Cloning of T-cell receptor genes (Tak
Mak 1984)
• Discovery of important genes:
- Alzheimers (St George-Hyslop 1995 )
- Cystic Fibrosis (Lap-Chee Tsui 1989)
- Parkinson’s disease (St George-Hyslop 1995)
• Regenerative medicine
Nanotechnology at Waterloo
• $120 million Quantum-Nano Centre for
quantum computing and nanotechnology
• The 225,000 sqft, professionally staffed
facility will house:
Quantum-Nano Centre: occupancy
date 2010
– The Institute for Quantum Computing
– 17,000 sqft of community laboratories for nano-metrology and nanofabrication
– More than 50 Quantum-Nano researchers
– 200 graduate students
– 500 undergraduate nanotechnology engineering students
Nanotechnology at Waterloo
• Waterloo’s nanotechnology faculty (30 existing,
21 newly created positions) specialize in:
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Nano-electronics & sensors
Integrated devices & systems
Energy storage
Nanostructured materials
Microlens arrays constructed to
enhance extraction efficiency of
quantum optoelectronic devices.
• Undergraduate nano-engineering co-op program
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5 year program launched in 2005
1st nanotechnology engineering undergraduate degree in Canada
Program includes 48 new courses specifically designed for nanotechnology
Senior year specializations include: nano-electronics, nano-materials,
nano-biosystems and nano-instruments
– Students spend a total of 24 months working in industry
Nanotechnology at the
Xerox Research Centre of Canada (XRCC)
• Commenced operations in 1974, with global mandate to develop
leading-edge materials for all of Xerox, from research concepts to
commercial reality – currently employs 120 scientists and engineers
• In June 2006, XRCC scientists reached 1000 US patent milestone
• XRCC nanotechnology strategy developed in mid-1990’s, and
recently updated to reflect:
– Injection of new technical competencies, being applied toward core as
well as new business applications
– Hired highly-skilled researchers with expertise in nanoscale science and
engineering
– Leveraging of nanotechnology partnerships with universities &
government to further expand our programs and facilities
Nanotechnology at the
Xerox Research Centre of Canada (XRCC)
– Project started in mid-1990’s, commercialized in
2001
– A bottom-up assembly process to grow micronsized toner particles from nano-sized building
block materials
– Enviro-friendly toner (less toner per printed
page) and lower energy toner manufacturing
process
– Over 20 Xerox products using this toner
Controlled
Growth
Precision
Designed
Toner at
Particle Level
1.1
1
Volume Differential
0.9
Number Differential
0.8
Normalized Count
• EA Toner Technology – XRCC’s first innovation
in nanotechnology:
Building up from
Individual
Atoms/Molecules
0.7
0.6
0.5
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0.2
0.1
0
1
10
Diameter (um)
100
Ontario-Alberta Partnership
• Xerox Research Centre of Canada, the National Institute for
Nanotechnology, the National Research Council of Canada and
the Government of Alberta will provide approximately $4.5 million
for research and development of materials-based nanotechnology
over the next three years
• Funds will contribute to the hiring of 6 – 10 scientists to investigate
materials-based nanotechnologies, including document and
display-related technologies
• Projects will be undertaken at both locations
• Collaboration will be jointly managed by Vice-President and
Director of Xerox Research Centre of Canada, and Director
General of NINT
Alastair M. Glass
Deputy Minister
NSERC Funding for Nano
• Includes:
$ Millions
Total NSERC Nano Funding
20
18
16
14
12
10
8
6
4
2
0
300
Funding - Canada
250
Funding - Ontario
# of PI's - Canada
– Salaries for
postdoctoral fellows,
graduate students,
technicians
200
# of PI's - Ontario
150
100
50
0
1996- 1997- 1998- 1999- 2000- 2001- 2002- 2003- 2004- 20051997 1998 1999 2000 2001 2002 2003 2004 2005 2006
– Associated costs of
doing research (lab
materials, facilities
access, conference
& publication fees)
• Does not include:
– university overhead
Year
PI = Principal Investigator
Approximately 40% of Canada’s NSERC funded
Principal Investigators engaged in nano
research are located in Ontario
– salaries of faculty or
permanent staff
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$ Millions
NSERC Funding by Province
8
7
2003-2004
2004-2005
6
2005-2006
5
4
3
2
1
0
NSERC Nano Funding by Application &
Province
2005 NSERC Nano Funding by Application
British Columbia
Equipment Purchases
Alberta
Quebec
Tools Development
Ontario
Life Sciences
Nanoelectronics/Nanophotonics
Materials Development
0
0.5
1.0
1.5
2.0
2.5
$ Millions
3.0
3.5
4.0
4.5
CIHR Nanomedicine Funding
CIHR Nanomedicine Funding
$12
Canada
$ Millions
$10
Ontario
$8
$6
$4
$2
$0
19992000
20002001
20012002
20022003
Year
20032004
20042005
20052006
CIHR Nanomedicine Funding by
Application
2005 CIHR Nanomedicine Funding by Application
5
Canada
$ Millions
4
Ontario
3
2
1
0
Biomaterials
Clinical Imaging
& Tool
Development
Drug Delivery
Molecular
Imaging &
Technology
Development