Transcript Organs for Research and Education

Organs for research
and education
Matthew Bock
When are organs used
for research?
Only after they have been determined unsuitable
for transplant
What makes an organ unsuitable for
transplant?


Performance
Condition
Performance
Kidneys
Creatinine
Liver
AST/ALT
Pancreas
A1C
Heart
Troponin, Echo
Lungs
X-ray, PO2
Condition



Fatty pancreas
Polycystic kidney
Fibrotic or fatty liver
If we can’t transplant…
There is still an option…
Research consent
Page 2 (back) of consent form
Page 2 (back) of consent form
Research consent for transplanted
organs

Liver study


Lung study


Biopsy
Bronch washings and blood ample
Kidney study
Order



1st - Transplant
2nd- In-house research
3rd - National
Order



1st - Transplant
2nd- In-house research
3rd - National
Order


1st - Transplant
2nd- In-house research


Pancreas islet cells
3rd - National
Order



1st - Transplant
2nd- In-house research
3rd - National
Order



1st - Transplant
2nd- In-house research
3rd - National


NDRI
IIAM
Who are NDRI and IIAM?

NDRI, National disease research interchange
IIAM, International Institute for the
Advancement of Medicine

Both are 501c non-profit

Heart
Heart, Arteries and Veins
Medical investigators use the human heart
to learn about the development of
atherosclerosis in coronary arteries
Kidneys
Renal tissues is used to study the toxicity of
anti-cancer therapies and to study the safe
concentrations of other drugs in development
Lungs
Research into chronic obstructive pulmonary
disease (COPD), cystic fibrosis, asthma,
emphysema and allergies
Pancres
Diabetes researchers rely on pancreatic tissues
to explore the regulation of insulin production,
to identify the genetic components of the
disease and for toxicity studies on new
compounds.
Liver


Hepatocyte cell isolation for transplantation
Human model for drug interaction, toxicity
and metabolism testing
Education

Whole body donation