Transcript Syn - hcopgnt

Antitussives
Tulsi
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DEPARTMENT OF TECHNICAL EDUCATION
ANDHRA PRADESH
Name
: R.D.L.P.Christian
Designation
: Lecturer in pharmacy
Branch
: Pharmacy
Institute
: GPW, Srikakulam(088)
Year
: I year
Subject
: Pharmacognosy
Subject Code
: PH-103
Topic
: Antitussives
Sub-Topic
: Tulsi
Duration
: 50 min.
Teaching Aids
: PPT, Photographs
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Recap
In the last class we learnt about
•
The plant drug TOLU BALSAM which can be used as
an Antitussive agent
• Tolu balsam mainly contain resinous substances
•
Having expectorant and Antitussive activity
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OBJECTIVES
On completion of this lesson, you would be able to
learn about
• The monograph of the Antitussive drug – TULSI
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Known to Unknown
1.
Which plant is called sacred plant?
2.
Do you find it is our Pharmacy garden?
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Antitussives - Definition
• Agents used in the symptomatic control of Cough
• Depress the cough centre present in the medulla
• Also termed as Anodyne, Cough suppressants and
Centrally acting Antitussives
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TULSI
Syn: Sacred basil, Holy basil, Tulasi (Telugu)
• Biological source :
Leaves of
Ocimum sanctum,
Ocimum bassilicum
• Family : Labiatae
• Geographical Source :
Annual herb found
throught India
Fig.40.1 Tulsi plant
(Holy Plant)
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Morphological Characters
LEAF
• Size
: 2 -5cm long
1.5-3.2 cm wide
• Type
: Simple
• Shape : Elliptic, oblong,
obtuse or acute
• Colour : Green
• Odour : Aromatic
Fig.40.2 Tulsi plant
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Morphological Characters
LEAF
• Taste:
Aromatic
• Apex:
Acute
• Margin:
Entire or serrate
• Base:
Obtuse or acute
• Petiole:
Slender
• Surface:
Pubescent on both sides
Fig.40.3 Tulsi plant
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Chemical Constituents
• Tulsi contains Volatile oil
• The oil contain about
70% Eugenol
20% methyl - Eugenol
β - Caryophyllene
Carvacrol
Cineole
Fig.40.4 Tulsi plant
Linalool
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Collection and Preparation
• The leaves contain bright yellow coloured and pleasant
Volatile oil
• The leaves and flowering tops are collected
• The oil is extracted by steam distillation
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Uses
Tulsi has variety of activities
• It is having Hypoglycemic,
Immunomodulatory, Antistress,
Analgesic, Anti-pyretic, Anti-hypertensive,
Anti-inflammatory, Anti-ulcer,
Anti-tumour activities
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Uses
• The expectorant and CNS depressant properties are
responsible for the
Antitussive properties
• The oil shows Antibacterial activity
against
Mycobacterium tuberculosis
Micrococcus pyogenes
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Summary
In this class we learnt about
The monograph of the Antitussive drug
TULSI
The active constituents is Volatile oil
Tulsi is having a variety of activities apart from
Antitussive activity
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Quiz
1. The chief Active constituent of Tulsi
a) Volatile oil
b) Resins
c) Latex
d) None of the above
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Quiz
2. The volatile oil of Tulsi is mainly present in
a) Roots
b) Stem
c) Leaves
d) None of the above
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Frequently Asked Questions
1.
Mention an anti-tussive drug with its source and
chemical constituents
2.
Write the chemical constituents and uses of Tulsi
3.
Write the Botanical source, morphological characters
and chemical constituents of Tulsi
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THANK YOU
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