Transcript Ketamine

Ketamine -
Effects
and Treatment
How Much Do You Know?
Michael Bird
Introduction
Ketamine is a drug used in human and veterinary
medicine developed by the pharmaceutical company
Parke-Davis (today a part of Pfizer) in 1962.
 Its hydrochloride salt is sold as Ketanest, Ketaset, and
Ketalar.
 Pharmacologically, Ketamine is classified as an
*NMDA receptor antagonist, and at high, fully
anesthetic level doses, Ketamine has also been found
to bind to opioid receptors and sigma receptors.
 The drug was first given to American soldiers during
the Vietnam War.
* NB not associated with MDMA

Group Exercise







I would like you to get into groups of no more than 5, use
the title ‘How much do we know about Ketamine’
For instance, you may wish to look at both it’s illicit and
legitimate usages
What is the ‘willing’ user of Ketamine trying to achieve?
What are the positive/negative effects of using Ketamine?
What treatment have you found to be useful, or have you
researched any successful treatment methods?
How would you currently work with someone that is using
Ketamine? What would be the care plan/referral pathway?
How would you define success with a Ketamine user?
So what are the Effects of
Ketamine?
Like other drugs of this class such as phencyclidine (PCP),
Ketamine induces a state referred to as *“Dissociative
Anesthesia” and is used as a recreational drug
 Ketamine has a wide range of effects in humans, including:
 Anesthesia - ‘blocking sensations’ inc. pain
 Analgesia - specific painkiller
 Hallucinations - distorted sensory experiences
 Bronchodilation - drug used to facilitate airflow
 Elevated blood pressure
* Slide on the term ‘Dissociative’ to follow

Medical Use





Ketamine is still used in human medicine as an anesthetic
and can be used in minor surgery
Used in treatment for complex regional pain syndrome
(CRPS)
Continued research into its effectiveness in treating
depression
Research into a combination of controlled Ketamine use,
Psychotherapy and Group Therapy as part of a treatment
program for Alcohol addiction.
Used in the treatment of Schizophrenia
What is Dissociative Substance?




A Dissociative is a drug which reduces (or blocks) signals
to the conscious mind from other parts of the brain,
typically, but not necessarily, limited to the senses.
Dissociation is a partial or complete disruption of the
normal integration of a person’s conscious or
psychological functioning
Such a state of ‘sensory deprivation’ or dissociation can
facilitate self-exploration, hallucinations and/or dreamlike
states of mind.
The risks and benefits of each dissociative experience, as
with most substances, are markedly different from user to
user.
Random Facts





Unlike other well known Dissociatives, i.e.PCP, the effects
of Ketamine are relatively short lasting - 15min/hour
dependant on amount and administration
Slang terms include Special K and being in a ‘K-hole’
As well as Most of the world's illicit Ketamine comes from
Asia-based pharmaceutical manufacturers, many ounces or
even kilos of pharmaceutical Ketamine are sold and
shipped in each transaction by legitimate Asian producers
100mg is usually enough to enter a K-hole
The price of Ketamine varies from £10 to £20 a gram.
Ketamine Treatment
Importance of a thorough assessment with a focus on:








Poly-drug use
Method of administration
Past successful treatments
Specific reason for this drug of choice and focusing on the
associated dangers of use
Assertive outreach may be needed for this hard to engage client
group
Set up specific groups - Meditation and Art/Music Therapy Groups
Alternative therapies inc Auricular Acupuncture
Long term engagement the most proven method for success
Final Questions




Can you identify any difficulties that you have currently
that may make things difficult for this client group? If so is
there anything that can be done to improve things?
Following the short discussion today, can you identify any
more effective ways of working with this particularly
difficult client group?
How can your team/group/agency improve the services
that you deliver to Ketamine users?
Is there anything further than I can do to help Ketamine
users?
Finally Thank You for your participation
Enjoy the rest of your day….