Transcript Marijuana

Intro Psych
States of Consciousness:
Drugs and Consciousness – Module 17
Apr 22-24, 2009
Classes #36-37
Drugs and Consciousness:
Altering consciousness with drugs
• In this final section on states of consciousness,
we will discuss some of the chemicals that alter
consciousness by inducing changes in
perception, mood, or behavior
– Because of their ability to alter psychological
processes, these chemicals are referred to as
psychoactive drugs
Altering consciousness with drugs…
• Psychoactive drugs are taken to achieve
a state of consciousness the user
considers to be positive, pleasant, even
euphoric
– No reasonable person would take a drug
because he or she expected to have a
negative or unpleasant experience
• Unfortunately, this is sometimes the
case
Psychoactive Drugs
• Any substance that alters:
– Mood
– Awareness of the external environment
– Awareness of the internal environment
• Examples:
– Marijuana, LSD, cocaine, heroine, alcohol,
nicotine, codeine, caffeine, etc.
Factors that influence the effects of drugs
• Dose-dependent effects
– The amount of the drug influences its effect
• Its intensity
• The kind of effect it has on the person
• Tolerance
• Refers to the lessened effect the drug will
produce with continued usage
– Cross-tolerance
• Can sometimes occur when one takes a certain
drug that then produces a tolerance in another
drug of that type
– Example: alcohol can produce a tolerance
for antianxiety drugs
Factors that influence the effects of drugs
• Interaction effects
– The effects of some drugs can be drastically altered if they are
taken in combination with other drugs
– The combination is often greater than what one might think the
sum of the two drugs would be
• Individual differences
– Chemical, personality, and experience differences will often cause
the same dosage of a drug to produce much different effects
depending on the individual who is taking it
• Expectations
– Psychological factor is often present as individuals sometimes
produce the effect that they expect the drug will produce
• People often get “drunk” on O’Douls
• Saline solution often stops pain in those thinking they are receiving a
pain killer
Types of Psychoactive Drugs
• Depressants
– Reduce physiological arousal and help individuals
to relax
• Opiates
– Have the effect of dulling or numbing the senses
– Can produce a sleeplike state
• Stimulants
– Increase arousal
– Produce states of arousal
• Hallucinogens
– Distort sensory experience
Depressants
• Alcohol
• Barbituates
• Benzodiazephines
Alcohol
• Alcohol is a depressant yet we often
feel lively after a couple of drinks…
– It gives this feeling by slowing down the
brain centers that control judgments and
inhibitions
Celebrities and athletes have high rates of
drinking problems…
Curious Effects
• Memory
• Sex
• Hangover
Alcoholism
• Refers to one’s dependence on alcohol that
seriously interferes with one’s life
• Most common and costly form of drug abuse
in U.S.
• Aproximately 7% of adults 18 and over (10M
people)
• Traditionally more common (about 2 to 1)
among males but recent research suggests
that women are closing this gap
Detrimental Effects
• Life span of average alcoholic is 12 years
shorter than the norm
• Alcoholism ranks as the third leading cause of
death in U.S.
• More than one-third suffer at least one
coexisting mental disorder
• Organic impairment such as brain shrinkage
occurs in a high proportion of alcoholics
• About 20% attempt suicide
• About 10% are successful
Symptoms of Alcohol Dependence
• Use alcohol to boost self-confidence and to
relax around others
• Drink to forget their problems or to relieve
stress
• Often are the ones who want “one more”
drink even when their friends have stopped
drinking
• After friends have left they drink with new
friends…often close the bar…stay past last call
• Get drunk without planning to
• Have blackouts
Symptoms of Alcohol Dependence
• Lie about their drinking, try to hide it,
sneak drinks at work or school
• Drink in the morning to cure a hangover
• May begin to have financial, work, or
family problems
• Complete loss of control
Treatments
• Rehab Centers
– Treatment centers where the addict is supervised 24/7
– Supervised detoxification period to eliminate drugs from our
bodies system
• Alcoholics Anonymous
– Self-help group
– Little research because of members anonymity but
indications are most don’t stick to it
– Need to go to regular meetings for it to work
– 90 meetings in first 90 days and then at least once per week
after that
• Antabuse
– A type of aversion therapy where usually a pill is taken that
will cause the patient to become sick whenever they drink
alcohol
Barbiturates
• Barbiturates are powerful depressants that
slow down the central nervous system
– Classified as sedative/hypnotics
• Once a very commonly used tranquilizer but
because they are highly habit-forming their
usage decreased
– They have effects similar to alcohol
– They depress sympathetic nervous system activity
– They have been used to induce sleep and reduce
anxiety
• In large doses, can lead to impaired memory
and judgment
Benzodiazepines
• Benzodiazepines (commonly referred to as
benzos) are a more recent generation of
tranquilizers
– Some of the more common
benzodiazepines are: ativan, librium,
valium, and xanax
– They are usually prescribed by doctors to
treat anxiety and sleep problems, they can
also, be used to treat panic disorders and
muscle spasms, and occasionally used in
the treatment of epilepsy and alcohol
withdrawal
Short-Term Effects
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Relaxation
Drowsiness
Dizziness
Confusion
Mood swings
Common Long-term Effects
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Lethargy
Irritability
Nausea
Loss of sexual interest
Increased appetite
Increased weight
Opiates
• Derived from opium these drugs depress CNS
functioning
• Include: opium, morphine, codeine, and
heroin
• Have the effect of dulling or numbing the
senses…
– Pupils constrict
– Breathing slows
– User becomes lethargic
• For a few hours, such things as pain and
anxiety are replaced by blissful pleasure
But for bliss you pay the price…
• Unfortunately, the bliss is eventually replaced
by a gnawing craving for another fix
• The need for progressively larger doses will lead to
the physical anguish of withdrawal if use is
discontinued
– If the user has taken opiates regularly, the
withdrawal symptoms may appear after only a few
hours have passed since the last dose and peak
after 2-3 days
– The symptoms include aches, nausea, fever,
trembling, convulsions, sweating and shivering.
• For some…the ultimate price to pay is death by
overdose
But for bliss you pay the price…
• The path to addiction is insidious…
– When repeatedly flooded with these
artificial opiates – the brain stops
producing its own natural opiates
(endorphins)
– So, when the drug is withdrawn, the brain
lacks the normal level of these painkilling
neurotransmitters
• The result is the raw agony of
withdrawal
Effects can be dangerous…
• Immediately after taking the drug the
user will experience a rush of euphoria
• Feelings of hunger and pain are
suppressed, along with sexual desire
• There is always a danger of an
overdose when the drug is bought on
the street as it is very difficult to
determine how strong the mixture is
– A fatal respiratory failure may develop
Stimulants
• Increase arousal and cause states of
euphoria that are generally referred to
as highs
• The two most powerful that are
abused:
– Amphetamines
– Cocaine
Amphetamines
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uppers
ups
wake ups
bennies
dexies
black beauties
jollies
speed
• An amphetamine is a drug that is a
stimulant to the central nervous system
Amphetamines
• Amphetamines are colorless and may be
inhaled, injected, or swallowed…
– These drugs may be used medically to
treat depression, obesity, and other
conditions
• Amphetamines are also used non-medically
to:
– Avoid sleep
– Improve athletic performance
– Counter the effects of depressant drugs
IMMEDIATE EFFECTS
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Increased talkativeness
Increased aggressiveness
Increased breathing rate
Increased heart rate
Increased blood pressure
Reduced appetite
Dilated pupils
Visual hallucinations
Auditory hallucinations
EFFECTS OF LARGE DOSES
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Fever and sweating
Dry mouth
Headache
Paleness
Blurred vision
Dizziness
Irregular heartbeat
Tremors
Loss of coordination
Collapse
• Death may also occur due to burst blood
vessels in the brain, heart failure, or very high
fever
LONG-TERM EFFECTS
• Mental illness similar to paranoid
schizophrenia…
– Amphetamine Psychoses
• Delusions like those seen in paranoid
schizophrenia– the long-term effect of high
doses cause an overproduction of dopamine
• Malnutrition due to suppression of appetite
• Increased susceptibility to illness due to poor
diet, lack of sleep and unhealthy environment
• Violence and aggression
• Multiple drug users may use other drugs to
counter unwanted side effects of
amphetamines
LONG-TERM EFFECTS
• Infections resulting from IV injections
• Blockage of blood vessels
• Tolerance and dependence
Methamphetamine
• A.k.a. meth
– A powerful stimulant drug,
classified as a psychostimulant
– One of today’s “drugs of choice”
– Very popular
– The alarming growth over the last
10 years and, in part, its popularity
can be explained by the drug’s wide
availability, ease of production, low
cost, and highly addictive nature
Why do people use meth?
• Initially, methamphetamine decreases fatigue
and appetite, heightens attention, and
increases activity and respiration, creating
feelings of high energy
• Meth enables people to stay awake and be
physically (also sexually) active for long
periods
How does meth work?
• Methamphetamine releases large
amounts of dopamine in the brain,
causing feelings of pleasure and euphoria
• Withdrawal symptoms may include
fatigue, depression, anxiety, paranoia,
aggression, and an intense craving for
more of the drug
• In some cases, psychotic symptoms may
persist for months or years following use
How is meth used?
• Injecting or smoking methamphetamine
produces a short but intense and pleasurable
“rush.”
• When taken orally or by snorting, meth
causes a less intense but much longer-lasting
high that persists for several hours.
Complications
• “Meth mouth” includes rampant caries (cavities)
due to the combined effects of meth’s acidic
nature, its xerostomic (dry mouth) effect, and
the tooth grinding and teeth clenching often
observed in meth addicts
• Added to these effects, methamphetamine use
often makes its users crave high-calorie (i.e.,
sugar-laden) soft drinks
WITHDRAWAL SYMPTOMS
• Amphetamines are addictive
– Because of this, when the user
discontinues use or reduces the amount
he/she uses, withdrawal symptoms may
occur
WITHDRAWAL SYMPTOMS
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Severe exhaustion
Deep sleep lasting from 24 to 48 hours
Psychotic reaction
Extreme hunger
Deep depression
Anxiety reactions
Long but disturbed sleep
Cocaine
• Effects are similar to amphetamines but
the rush is much more intense…
– SLANG TERMS
• Coke
• Crack
• Dust
• Snow
• Blow
• Flakes
• Bloke
• Bernice
• Dream
Cocaine
• Cocaine is an addictive substance which
comes from coca leaves or is made
synthetically
– This drug acts as a stimulant to the central
nervous system
– Cocaine appears as a white powder substance
which is inhaled, injected, freebased (smoked), or
applied directly to the nasal membrane or gums
– Cocaine gives the user a tremendous "rush“
– These chemicals trick the brain into feeling it has
experienced pleasure
PHYSIOLOGICAL EFFECTS
• Increased
– Heart Rate
– Breathing
– Blood pressure
• Nausea
• Weight loss
• Tremors
• Insomnia
• Rapid breathing
• Twitching
• Fever
• Paleness
PHYSIOLOGICAL EFFECTS
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Sexual problems (impotence)
Dilated pupils
Cold sweats
Fatigue
Constipation
Headaches
Blurred vision
Seizures
Nasal congestion
PERSONALITY EFFECTS
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Lying
Stealing
Superior attitude
Less ambition
Argumentativeness/short temper
Job problems
Denial of responsibility
Depression
PERSONALITY EFFECTS
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Confusion
Increased number of accidents
Hallucinations
Anxiety
Paranoia
Poor concentration
Loss of interest in sex
Flattened and dulled emotions
Addiction
• The effects of cocaine occur within the first
few minutes, peak in 15-20 minutes and
disappear in about 1 hour
• The immediate effects are what make cocaine
so addicting
• The user is willing to endure the lows in order
to experience the highs
• Cocaine is highly addictive
• Every use of the drug makes the addiction
stronger
Hallucinogens
• Marijuana
• LSD
• PCP
Marijuana
• About 1 in 3 Americans
has used marijuana at
least once and
approximately 10% of the
population uses it on a
regular basis
• Next to tobacco and
alcohol, marijuana is the
most popular substance
chosen by young people
for regular use
Marijuana
• Triggers a mixture of effects that
makes this drug difficult to
classify…
– Like alcohol it has a depressant effect…
• It relaxes, disinhibits, impairs motor
coordination
– It is also a mild hallucinogen
• It can slow the passage of time and
amplify one’s sensitivity to colors,
sounds, tastes, and smells
Marijuana
• Dried leaves of the cannabis plant
• Usually smoked, but can be eaten in
cookies, candy or brownies
• Marijuana’s effects vary widely from
person to person
– Mood swings from “placid dreaminess to
euphoric gaiety”
– Negative mood swings are rare
Marijuana
• Effects cognition…
– Users believe that things are more
interesting, more profound, that they are
more creative
• Research has shown this is not the case
– Increased distractibility
– Decline in short term memory
Marijuana
• Very quickly absorbed into the bloodstream
when smoked
• Takes longer when eaten, but the effects last
longer as well
• Effects physical coordination and perceptual
abilities
– Not much different than alcohol when it comes to
driving…probably should stay away from heavy
equipment too…
LSD (Lysergic acid diethylamide)
• Causes a disruption of serotonin brain
receptors and this leads to
hallucinations
• It comes in a variety of forms but is
virtually always taken orally
Effects
• Onset
– Generally 20-60 min.
• Duration
– Primary effects last 6-8 hrs.
• Experience
– Beginning is a sort of anticipation, then a slight
energy surge, something is different feeling, lights
may seem to have an extra twinkle, then effects get
stronger – feelings of insight, confusion, paranoia,
and quickly changes emotions (happiness to fear to
joy to irritation, etc)
Problems
• Although a euphoric state is often achieved,
LSD users must be prepared for a “bad trip”…
– Recent experiences such as unsettling events
during the day can blossom into more serious
distress and trauma while tripping
– A “bad trip” can produce vividly, terrifying
images…so much so that its possible for someone
to jump out of a window in order to get away
from these images
– Very important for these drug users to take
precautions so that tragedies can be averted
Problems
• Post-hallucinogen perceptual disorder
– At least 5% of LSD users experience LSD
flashbacks…
– Sudden, uncontrollable recurrences of perceptual
distortions like those experienced on a “trip”
– Person “freaks out” because they have no clue
what is happening to them
– May become chronically anxious because of this
– Seems that the drug is stored somewhere in the
body and later released
• Using LSD can result in chromosomal damage
Problems
• Some people become psychologically
dependent on LSD
– Not usually physiologically addictive though
PCP (Phencyclidine)
• Commonly referred to as “angel dust” this
substance is often sprinkled over dried
parsley, oregano, or marijuana leaves, it can
be smoked and effects noted within 2 to 5
minutes, then peaking at 15 to 30 minutes
• Taken orally, in the pill form or mixed with
food or beverages, PCP's effects are usually
noted within 30 minutes and tend to peak at
about 2 to 5 hours
Angel Dust
• Lower doses of PCP typically produce euphoria and
decreased inhibition as may be seen with
drunkenness
• Mid-range doses cause body wide anesthetic with
enhanced sensations and impaired perceptions which
may result in panic reactions and violent defensive
behaviors
• Large doses may produce paranoia, auditory
hallucinations, psychosis similar to schizophrenia
• Massive doses, more commonly associated with
ingesting the drug, may cause cardiac arrhythmias,
seizures, muscle rigidity, acute renal failure, and
death
– Because of the analgesic properties of PCP, users who incur
significant injuries may not feel any pain
Near-Death Experiences…do we
really have them???
• Gallup (1982)
– Huge nationwide survey
– 15% reported having a close brush with
death
– One-third of these (8 million people) reported
having a mystical experience in connection
with it
Siegel (1977)
• Many similarities between “near-death” experiences and typical
hallucinogenic experiences
– Visions of tunnels or funnels
– Bright lights
– Beings of light
– Replay of old memories
– Out-of-body sensations
Near-Death Experiences
• Often, oxygen deprivation is occurring during
injuries to the brain – these are known to
produce hallucinations
• Since reports are always of a positive nature…
• Interesting note:
– Some researchers have interviewed people who
have experienced both and say that these people
deny their similarities
– In addition, those in the near-death experience
are permanently changed by the experience which
is not the case with hallucinations
– They usually become kinder, more spiritual people