Transcript DOTS-Plus Operational Research

Current research areas in DOTS Plus
1. Quality assurance of DST to second-line drugs
and resistance criteria for second-line drugs
2. New diagnostics to detect drug resistance
3. Transmissibility and fitness of MDR-TB strains
4. Acquisition of drug resistance
5. Impact of HIV epidemic on MDR-TB epidemic
6. Management of MDR-TB
7. Economic evaluation of DOTS Plus
8. Availability of second-line drugs