Transcript Narcan Overview - Telco House Bed & Breakfast

NARCAN OVERVIEW
Narcan
Classification—Synthetic opioid antagonist
Mechanism—Competes for opioid receptor sites.
Displaces previously administered opioids from
their receptors.
Indications—Opioid induced collapse;
hemodynamic instability and respiratory
depression
-Cardiovascular collapse with airway
compromise and a differential diagnosis of drug
abuse
Narcan
Contraindications—Hypersensitivity to
Naloxone (Morphine-like opioids)
Dose--Unconscious/overdose: 0.4 mg IV or 0.8
mg SC
Route and Methods of Administration—IV
push; repeat as indicated (per protocol) SC;
repeat as indicated (per protocol)
Narcan
Onset, Duration—Less than 2 minutes 30 to 60
minutes (IV)
Elimination—Liver; half-life of 60 to 90 minutes
(IV)
Narcan Side Effects:
CNS--Excitation due to abrupt
reversal of analgesia
-Tremulousness
CVS—Tachycardia
-Hypertension
-Arrhythmias
Skin--Sweating
Narcan Special
Considerations
 Can cause abrupt state of narcotic withdrawal in
the physically dependent patient.
 Side effects such as agitation and aggressiveness
can be symptoms of narcotic withdrawal.
 Naloxone's half-life (60 to 90 minutes) is shorter
than that of all opioids; therefore, a patient must
be observed until the narcotic effect has worn
off.
 All patients treated with Naloxone must be
transported to hospital
Commonly Abused Opiates
 Codeine
 Heroin
 Hydromorphone
(Dilaudid)
 Morphine
 Fentanyl
 Demerol
 Opium
 Amileridine (Leritine)
 Pentayocine (Talwin)
 Methadone
 Percocet (Percodan)