Transcript COURSE OBJECTIVES - Chemical Engineering

PHARMACEUTICAL TECHNOLOGY
B. Amsden
CHEE 440
COURSE OBJECTIVES
Introduce the fundamentals of preparing dosage forms.
Demonstrate the application of engineering and applied science
fundamentals to large scale production of dosage forms.
Prepare student for an engineering position in the pharmaceutical
industry.
B. Amsden
CHEE 440
COURSE OUTLINE
Introduction
• the need for delivery systems
Principles of Drug Absorption
• routes and mechanisms
• pharmacokinetics
Solid Dosage Forms: Tablets, Capsules
• unit operations
• drug stability issues
Solutions, Suspensions, Emulsions
Good Manufacturing Practices
B. Amsden
CHEE 440
Problem Sets and Tutorials
Study problem sets are not marked:
 to aid in understanding material
 solutions will be posted weekly
Tutorials:
• Run by the TA (s)
• Problem posed and answered in class
B. Amsden
CHEE 440
GRADING
Midterm Exams (2) 50 %
Held during class time (1.5 h each)
Midterm 1: Feb 9th, 2012
Midterm 2: March 15th, 2012
Final Exam
B. Amsden
50 %
CHEE 440
COURSE MATERIALS
Recommended textbook
 Pharmaceutics: The Science of Dosage Form Design, 3rd
Ed., M.E. Aulton Editor, 2007.
Other useful books:
 Remington: The Science and Practice of Pharmacy, 21st Ed.,
2005
 Pharmaceutical Dosage Forms and Drug Delivery Systems,
6th Ed. 1995
 Perry’s Chemical Engineers’ Handbook
Lecture notes
 www.chemeng.queensu.ca/courses/CHEE440/lectures/index.php
B. Amsden
CHEE 440