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Update from the Division of
Epidemiology, Services and
Prevention Research
Wilson M. Compton, M.D., M.P.E.
Director, Division of Epidemiology, Services and Prevention Research
National Institute on Drug Abuse
Department of Health and Human Services
DESPR provides a
foundation for NIDA’s
Public Health Mission.
DESPR will improve the nation’s
public health by promoting
integrated approaches
to understand and address interactions
between individuals and environments
that contribute to the
continuum of problems
related to drug use.
Our goal is to develop scientific knowledge with
clear application to practice and public policy.
DESPR Organization
EPIDEMIOLOGY
RESEARCH
BRANCH
OFFICE OF THE
DIRECTOR
ANALYTIC UNIT
SERVICES
RESEARCH
BRANCH
WORKGROUPS
AIDS/HIV
Health Disparities
Translational Research
Research Training
PREVENTION
RESEARCH
BRANCH
DESPR: Five Year Goals
1. Measurably impact public health
prevention and treatment outcomes
2. Demonstrate the role of interactions
between intrapersonal and environmental
factors with each other and with genetic
factors
3. Develop transdisciplinary research teams
to better elucidate this chronic condition,
its prevention and treatment
Priority Areas for NIDA
• Prevention Research (Children/Adolescents)
–
–
–
–
Genetics
Development
Environment
Co-morbidity
• Treatment Interventions
– New Targets & New Strategies
• HIV/AIDS Research
Preventing and Treating Drug Abuse and
Addiction Require Multi-Pronged Approaches
genome
protein
expression
DRUGS OF ABUSE
social
Behavior
neuronal circuits
Distribution of Selected Drug Abuse
Related Variables by Race/Ethnicity
100%
11
11
12
11
80%
4
3
1
15
18
23
5
6
16
60%
43
40%
74
70
50
65
20%
35
26
0%
p
Po
n
io
t
a
ul
fe
Li
tim
e
U
se
A
White
bu
/D
e
s
e
ep
nt
e
nd
Black
is
Pr
s
er
n
o
ID
Hispanic
U
s
/H
w
Other
-A
IV
ID
S
FY 2004 RFAs/Contracts
1. Prevention and Treatment of Drug Abuse in
Primary Care Settings
FY04 $3.0m RFA with SAMHSA and AHRQ
2. Environment-Gene Interaction Studies
FY04 $2.0m RFA
3. Young Adult Prevention
FY04 $1.5m RFA, meeting January 2004
4. HIV/AIDS Among Drug Users in Criminal Justice
FY04 $1.5m RFA
5. Studying CSAP’s Strategic Prevention Plan
FY04 $2.5m IAA, meeting March 2004
Environmental Challenges/Opportunities
•
•
•
•
New NIDA Organization
Budget flattening
NIH Roadmap
Improved Collaborations with SAMHSA,
DOJ and Education
• At Other ICs:
– NIMH reduced support of longitudinal studies
– NIAAA re-organization of Services Research
Themes for DESPR in FY 2005
1. Maximize Return on Investment
2. Rethink the Social Environment
3. New Issues in the Emerging
HIV/AIDS - Drug Abuse Nexus
4. Translational Research
What are we doing to
develop and promote these
themes?
Workgroups, Meetings, Publications, etc.
Rethinking the Social Environment: Integrating
Social and Genetic Epidemiology With Neuroscience
Social Epi
Genetic Epi
Summer-Fall 2004:
Identification of
datasets/studies ripe for nesting
December 2004:
Neuroscience
Special Supplement AJPM
Spring 2005:
Midsize meeting
Summer-Fall 2004:
Portfolio & literature review
Fall 2004:
Small meeting
Spring 2005: Phenotype
Special Issue JSA
Fall 2005
Social Epi
Transdisciplinary Meeting
Future Initiative
Genetic Epi
Community
Bedside
Bench
Community
Bedside
Bench
Interagency
Collaborations
are indispensable
DHHS
NIH
SAMHSA
NIDA
Collaborations to Translate Research
Findings Into Relevant Clinical Practice
Science to Services Cycle
Community
Bedside
Bench
Working in “RealWorld Settings”
is key.
Testing the Commuties That Care
(CTC) Prevention System
Research Centers
Coordinating Center
Community
Bedside
Bench
Developing the Health
Services Research
Program
Rec #1: Defining Health Services Research
A multidisciplinary field that examines how:
social factors,
financing systems,
access to and utilization of
healthcare,
organizational structures
and processes,
quality and cost of
healthcare, and
health technologies, and
affect
our health and well-being.
personal beliefs and
behaviors
Ultimately, the goals of health services research are to
identify the most effective ways to organize, manage,
finance, and deliver high quality care.
Division of Epidemiology, Services and
Prevention Research
Providing a foundation for
NIDA’s public health mission.