Transcript Slide 1

Tips on how to present research
findings (dichotomous data)
January 2010
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Shingles Prevention Study – Results
Outcome
Herpes zoster
overall
Herpes zoster
age ≥ 70
Event rate
Placebo
Zostavax
3.3%
1.6%
3.5%
2.2%
RRR
51%
37%
ARR
1.7%
1.3%
Reference text box
Time
NNT
(Yrs)
95% CI
4 yrs
4 yrs
59
50 – 72
77
56 – 124
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Shingles Prevention Study – Results
Outcome
Herpes zoster
overall
Event rate
Placebo
Zostavax
3.3%
1.6%
RRR
ARR
51%
1.7%
Time
NNT
(Yrs)
95% CI
4 yrs
Herpes zoster
age ≥ 70
3.5%
2.2%
37%
1.3%
4 yrs
PH neuralgia
overall
0.42%
0.14%
66%
0.3%
4 yrs
PH neuralgia
age ≥ 70
0.64%
0.21%
67%
0.4%
4 yrs
Reference text box
59
50 – 72
77
56 – 124
363
263 – 587
234
162 – 425
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ARBs – Reductions in HF Hospitalizations
Outcome
Hospitaliz’ns
(candesartan)
Hospitaliz’ns
(valsartan)
Event rate
Placebo
Drug
24%
20%
18%
14%
RRR
ARR
18%
4%
24%
4%
Reference text box
Time
NNT
(Yrs)
95% CI
3.5 yrs
2 yrs
23
16-41
23
15-42
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Event rate 24% vs 20% - Hosps
RRR
18%
ARR
4%
NNT
23 (14 – 41) 3.5 yrs
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Questions or Further Help
Dr Mike Allen
Director Evidence-based Programs
Dalhousie CME
494-2173
[email protected]
For supportive tools visit:
http://cme.medicine.dal.ca/EBM.htm
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