Transcript UniProtKB/Swiss-Prot

Swiss-Prot group activities
www.uniprot.org
www.expasy.org
Swiss Institute of Bioinformatics – Geneva
in collaboration with the UniProt Consortium
The main focus of the Swiss-Prot group is to provide the scientific community with the most accurate
protein sequences associated with a high level of functional annotation, in an user friendly format allowing
easy data retrieval and analysis. The group is involved in the production of the manually curated
UniProtKB/Swiss-Prot knowledgebase (www.uniprot.org),
the ENZYME nomenclature database (http://www.expasy.org/enzyme) ,
the protein families and domains PROSITE database (http://www.expasy.org/prosite)
and the taxonomy database (http://www.uniprot.org/taxonomy/)
Protein Annotation Programs
-
Vertebrates (CD2)
Bacteria and Archae (HAMAP)
Plants (PPAP)
Fungi (FPAP)
Viruses
Dictyostelium discoideum
Drosophila and C.elegans
Toxins (Tox-Prot)
-
Controlled vocabulary (GO annotation)
Post-translational modifications (PTMs)
Integration of proteomic data
Integration of 3D structure information
Human polymorphisms and diseases
Quality Assurance
Software development
Research
- Annotation platform development
and maintenance
- UniProtKB/Swiss-Prot release
- ExPASy and UniProt websites
Service, education and popular science
- Calipho
Computer Analysis and Laboratory Investigation of Proteins of Human Origin
- Phylogeny
- User support
- Courses and tutorials (e-Proxemis)
- Master in Proteomics and Bioinformatics
- Doctoral school (SIB)
- Text mining
- Sequence analysis tool development
- Knowledge management of human
variants
Contact
Swiss-Prot group
Swiss Institute of Bioinformatics
Centre Médicale Universitaire
1 Michel Servet
1211 Geneva 4
Phone: + 41 22 379 50 50
Fax: + 41 22 379 58 58
[email protected]
- Protein Spotlight
(www.expasy.org/spotlight/)
- Protéines à la ‘Une’
(www.expasy.org/prolune/)
Electronic
publications
The team
Amos Bairoch and Lydie Bougueleret
(group leaders)
50 annotators (life science background),
13 programmers, 8 reseachers,
15 persons involved in system
administration, service/education and
administration.
The Swiss-Prot group is part of the Swiss Institute of Bioinformatics (SIB) and of the UniProt Consortium.
Swiss-Prot group activities are supported by the Swiss Federal Government through the Federal Office of Education and
Science and by the National Institutes of Health (NIH) grant 2 U01 HG02712-04. Additional support comes from the
European Commission contract FELICS (021902RII3) and from the PATRIC BRC (NIH/NIAID contract HHSN
266200400035C).
Swiss Institute of Bioinformatics (SIB)
European Bioinformatics Institute (EMBL-EBI)
Protein Information Resource (PIR)
www.uniprot.org