Transcript Indonesia
Natural Resources for our Healthy and Prosperous Generation Subagus Wahyuono Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia Indonesia East West Central Indonesia is an archipelago comprising of approximately 17,508 islands. It encompasses 37 provinces with about 250 million people, making Indonesia is the world's fourth most populous country We are blessed by the richnest of biodiversity on the world. This is one of Biodiversity Hot spots in Indonesia Nicotiana tabacum Papaver somniverum Salix alba Diospyros kaki (kesemek) Taxus brevifolia Garlic Traditional Medicine has been Practiced in Indonesia TRM practice Raw materials traditionally used 1st lady Registered Jamu preparation Herbal Product Symbols Jamu Godog INTEGRATED MEDICINE HARMONIZATION WESTERN MODERN MEDICINE STANDARDIZATION TRADITIONAL MEDICINE Way to “Health for All ” Searching Potential Biodiversity from Central Kalimantan, guided by local medicine man • 105 species were collected according to local Medicine Man, consisting of: – 3 families (Lycopodiaceae, Gleicheniaceae, Polypodiaceae) of Pteridophyte – 42 families of Spermatophyte 8-oxoprotoberberine HeLa Cells (20.08%) inhibited in vitro by this compound (500 µg/ml). • Yellow roots (Male) • Arcangelisia flava (L.) Merr. (Fam. Menispermaceae) • Cure Liver deseases • Yellow roots (Female) • Fibraurea chloroleuca Miers. (Fam. Menispermaceae) • Cure Liver deseases • Renta (Local name) • Combretum acuminatum Roxb. (Fam. Combretaceae) • Protection for pregnant woman from Magic. • Sinduk (Local name) (Garlic odor when the leaves craushed) • Scorodocarpus borneensis Becc. (Fam. Olacaceae) • Stomachache, antiflatullent • Saluang belong Male (local Name) • Dictamnus albus L. (Fam. Rutaceae) • Sexual enhancement for Men • Pasak bumi/Tongkat Ali • Eurycoma longifolia Jack. (Fam. Simaroubaceae) • Sexual enhancement for men • Tapak barito (Local Name) • Ficus deltoidea Jack. (Fam. Moraceae) • Habitus : epifit • Sexual enhancement for women • Serai hutan (Local name) • Celtis cinnamomea Lindl. ex Plancho (Fam. Ulmaceae) • Smell likes Lemon Grass (Gramineae) THE ROLES OF NATURAL RESOURCES FOR HUMAN HEALTH AND PROSPERITY Marine chemistry Human biochemistry Flora, Animals Microorganisms Principal Active Compounds PHYTOPHARMAKA (Plants) (Curative) Chemopreventive, Chemoprotective (Prevention) DRUGS (Curative) Methyl gallate Multi-stage of carcinogenesis Curative v/s Preventive Procarcinogen Metabolic activation Secretion Kuratif Ultimate Carcinogen Promotion (> 10 thn) Initiation (1-2 days) Normal cells Initiated cells Progression (> 1 thn) Preneoplastic cells Neoplastic cells PRO-TECT : A product provides a broad spectrum flavonoid complex Pro-tect : Provides broad spectrum antioxidant nutrition of flavonoid. Pro-tect : Provides flavonoids present in the 8 standardized-qualified extracts Flavonoid : a phenolic type of compound present in plants, responsible for the bright colors of fruits, vegetables, useful for health promotion. Pro-Tect contains : Pycnogenol dan grape seed extract Redbilberry extract Grape skin extract Green tea extract Ginkgo biloba extract Milk thistle (Sylibum marianum) extract Citrus bioflavonoids Red Billberry Gyngko biloba Silibum marianum Silimarin Utilize the waste of carrot (Daucus carota) leaves Lutein (a carrotenoid type of compound) Scientific data is a must Proton NMR Lutein OPTIMATION OF KESEMEK (Diospyros kaki Thunb.) LEAVES AS SUPPLEMEN PRODUCT TO PROMOTE HEALTH • This sp. grows well in the northern of TNGM (Merapi Mt National Park) • The fruits have economic values for people • The leaves are discarded • How to optimize economic values of the plant benefit for people surrondings Similarity Index 79,2 % Similarity index 20,8 % Modern Medicine, Taxol Herbs Garden But please not this kind of product..... Herbal Medicine Products Thank you for your attention Research Laboratory Dept. of Pharmaceutical Biology Faculty of Pharmacy, GMU Unit-2, 1st floor E-mail: [email protected]